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冠心病患者血脂及血浆同型半胱氨酸的临床意义

Clinical Significance of Plasma Lipid and Homocysteine in Patients with Coronary Disease

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【作者】 王广兴孙华保李泽林

【Author】 WANG Guang-xing,SUN Hua-bao,LI Ze-lin Department of Cardiology,Central People’s Hospital of Zhanjiang,Guangdong Province,524037

【机构】 广东省湛江中心人民医院心内科

【摘要】 目的:探讨血脂及血浆同型半胱氨酸(Hcy)在冠心病发生过程中的临床意义。方法:比较冠心病组110例和正常对照组78例的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、Hcy、叶酸及维生素B12水平。结果:冠心病组的TC、LDL-C和Hcy水平较对照组高,叶酸及维生素B12水平低,差异均有统计学意义(P<0.05);多因素Logistic回归分析显示与冠心病有关的因素是LDL-C和Hcy。结论:高LDLC和高Hcy水平均为冠心病发病相关的独立危险因素,对冠心病的诊断有一定的临床价值。

【Abstract】 Objective:To explore the clinical significance of plasma lipid and Hcy in patients with coronary disease.Methods;TC,TG,LDL-C,HDL-C,Hcy,folic acid and vitamin B12 level were compared between the coronary disease group(n=110) and control group(n=78).Results;Compared with the control group,the TC,LDLC and Hcy level were higher,and folic acid and vitamin B12 level were lower with significant differences,P<0.05. Multivariate logistic regression analyses showed that LDL-C and Hcy were significantly associated with coronary disease.Conclusion;LDL-C and Hcy are the independent risk factors of coronary disease and having diagnostic value for coronary disease.

【关键词】 冠心病血脂同型半胱氨酸
【Key words】 coronary diseaselipidhomocysteine
  • 【文献出处】 岭南急诊医学杂志 ,Lingnan Journal of Emergency Medicine , 编辑部邮箱 ,2012年05期
  • 【分类号】R541.4
  • 【下载频次】11
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