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640例脊柱肿瘤及瘤样病变的临床流行病学分析

A epidemiological analysis of 640 cases of tumors and tumor-like lesions of spine

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【作者】 张小军王臻郭征李靖王海贤

【Author】 ZHANG Xiao-jun,WANG Zhen,GUO Zheng,LI Jing,WANG Hai-xian.Department of Orthopaedic Surgery,People’s Hospital of Tongchuan,Tongchuan 727000,China

【机构】 铜川市人民医院外二科第四军医大学西京骨科医院骨肿瘤科

【摘要】 目的总结临床常见脊柱肿瘤及瘤样病变的流行病学发病情况及构成比。方法通过对西京骨科医院骨肿瘤科和铜川市人民医院骨科1990年至2007年收治的640例脊柱肿瘤及瘤样病变患者资料进行统计学分析,观察临床各种常见脊柱肿瘤的构成比及其在不同年龄、性别及部位的发病情况。结果 640例脊柱肿瘤及瘤样病变中良恶性之比为0.62∶1;良性与恶性肿瘤男女性别比为1.11∶1与0.77∶1;年龄分组中良性肿瘤好发于31~40岁和41~50岁,恶性肿瘤及转移瘤好发于51~60岁和>60岁;发病率从高到低依次为:转移瘤、神经鞘瘤、脊索瘤、骨髓瘤、骨巨细胞瘤、神经纤维瘤,其中脊柱恶性肿瘤最常见的是转移瘤,原发恶性肿瘤中最常见为脊索瘤,其次为骨髓瘤。良性肿瘤最常见为神经鞘瘤,其次为骨巨细胞瘤;良性肿瘤的好发部位为腰椎,恶性肿瘤的好发部位为骶椎和腰椎,转移瘤好发部位为胸椎。结论在脊柱肿瘤及瘤样病变中,以恶性多见,尤其是转移瘤高发;男女性别无明显差异;转移瘤好发于60岁以上患者。

【Abstract】 Objective To analyze and summarize the epidemiology and constituent ratio of spinal tumors and tumor-like lesions in the clinical cases.Methods The constituent ratio of all kinds of common spinal tumors and incidences of diseases in different ages,sexes and positions were observed,through statistical analysis of 640 cases including spinal tumors and tumor-like lesions in bone tumor department of Xijing Orthopedics Hospital and orthopedics department of People’s Hospital of Tongchuan for 18 years from 1990 to 2007.Results The ratio of benign and malignant tumors in 640 cases was 0.62∶1;the sex ratios of benign and malignant tumors were 1.11∶1 and 0.77∶1 respectively;31 to 40 and 41 to 50 were the commonest onset ages for intermediate benign tumors and 50 up for malignant tumors and metastases in the age groups.Incidences from high to low as follows: metastatic tumors,neurinoma,chordoma,myeloma,giant cell tumor of bone,neurofibroma,among which metastatic tumor was the commonest case in spinal malignant tumors.Chordoma was the commonest among primary malignant tumors followed by myeloma.Neurinoma was the commonest in benign tumors followed by giant cell tumor of bone.Lumbar vertebra was the common position of benign tumors,while sacral and lumbar vertebras were the common positions of malignant tumors.Thoracic vertebra was the place of metastatic tumors.Conclusion Malignant tumors frequently exist in the spinal tumors and tumor-like lesions,especially in metastatic tumors.There is no difference between sexes for malignant tumors,but they are likely to attack people over 60 years old.

【关键词】 脊柱肿瘤构成比流行病学
【Key words】 Spine tumorsConstituent ratioEpidemiology
  • 【文献出处】 临床肿瘤学杂志 ,Chinese Clinical Oncology , 编辑部邮箱 ,2012年06期
  • 【分类号】R738.1
  • 【被引频次】19
  • 【下载频次】322
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