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89例慢性淋巴细胞白血病免疫表型的检测与分析
Research on immunophenotype of 89 cases of chronic lymphocytic leukemia
【摘要】 目的:研究慢性淋巴细胞白血病(CLL)免疫表型的特点。方法:采用流式细胞仪(FCM)分析89例CLL的免疫表型特点。结果:大部分CLL表达CD5、CD19、CD23;CD79b表达率也较高;部分表达CD38和ZAP-70。结论:免疫表型的检测对于CLL的诊断和预后有重要价值。
【Abstract】 Objective:To investigate the characteristics of immunophenotype of chronic lymphocytic leukemia(CLL).Method:Flow cytometry was used to detect the immunophenotype of 89 cases CLLs.Result:The CLL typically expressed CD5,CD19 and CD23.CD79b could be detected on CLL cells of the majority patients.CD38 and ZAP-70 could be detected on some CLL cases.Conclusion:The immunophenotype analysis might be important in CLL diagnosis and CLL prognosis evaluation.
【关键词】 白血病,淋巴细胞,慢性;
免疫表型;
评价;
【Key words】 lymphocytic leukemia; chronic; immunophenotype; evaluation;
【Key words】 lymphocytic leukemia; chronic; immunophenotype; evaluation;
【基金】 上海市卫生局科研项目(No:2010079)
- 【文献出处】 临床血液学杂志 ,Journal of Clinical Hematology , 编辑部邮箱 ,2012年04期
- 【分类号】R733.72
- 【被引频次】17
- 【下载频次】751