【摘要】 目的:分析急性冠状动脉(冠脉)综合征(ACS)患者血清胱抑素C(CysC)和白细胞介素6(IL-6)水平变化及临床意义。方法:选择2010-08-2011-12我院住院患者102例,分为急性心肌梗死(AMI)组30例、不稳定型心绞痛(UAP)组45例、稳定型心绞痛(SAP)组27例;另选取77例非冠心病(CHD)住院患者为非CHD组。分别测定各组血清CysC与IL-6水平,组间进行两两比较。结果:UAP组血清CysC水平明显高于SAP组及非CHD组;AMI组血清CysC水平较UAP及SAP组低,与非CHD组比较差异无统计学意义。IL-6水平分别为:AMI组>UAP组>SAP组>非CHD组。结论:CysC与IL-6可能与ACS的发生发展有关,早期联合检测CysC与IL-6对预测ACS的发生和发展有一定指导意义。更多还原

【Abstract】 Objective:To study the change of serum Cystatin C(CysC) and IL-6 levels and its clinical significance in patients with acute coronary syndrome(ACS). Method:One hundred and two patients with CHD from August 2010 to December 2011 were selected and divided into acute myocardial infarction(AMI) group,unstable angina(UAP) group and stable angina(SAP) group.Seventy-seven patients without CHD were selected in non-CHD group.The level of CysC and IL-6 were detected. Result:The level of CysC in UAP group was higher than that in non-CHD group and SAP group(P<0.05).The level of CysC in AMI group was lower than that in UAP group and SAP group(P<0.05),and there was no significant difference between in non-CHD group and AMI group(P>0.05).The levels of IL-6 from high to low order were AMI group,UAP group,SAP group and non-CHD group. Conclusion:The expression of CysC and IL-6 may play a key role in the occurrence of ACS.Detecting CysC and IL-6 levels have a certain guiding significance in prediction of ACS occurrence.更多还原