【摘要】 目的探讨急性心肌梗死(AMI)延迟冠状动脉介入治疗(PCI)的临床效果。方法将106例AMI患者按随机数字表法分为2组,药物治疗组50例,采用常规药物(肠溶阿司匹林、氯比格雷、他汀类调脂、低分子肝素,据情况予硝酸酯类、血管紧张素转换酶抑制剂、β受体阻滞剂等)治疗;PCI组56例,经药物治疗7～15d后PCI。1年后对2组患者病死率和再发心梗、心绞痛的发生率以及左室射血分数(LVEF)水平的变化进行比较。结果 PCI组再发心梗、心绞痛的发生率明显低于药物治疗组,LVEF明显高于药物治疗组(P<0.05或P<0.01)。结论 AMI延迟PCI能改善患者的预后。更多还原

【Abstract】 Objective To investigate the clinical effects of medicine therapy and delayed percutaneous coronary intervention(PCI) on acute myocardial infarction(AMI).Methods A total of 106 patients with AMI were randomly divided into two groups.Medicine therapy group(n=50)was treated with conventional drugs(aspirin,clopidogrel,statins,low molecular weight heparin,nitrates,angiotensin converting enzyme inhibitors,β-receptor blockers,etc.).PCI group(n=56)was given delayed PCI after drug treatment for 7~15 days.The mortality,recurrence of myocardial infarction,incidence of angina and left ventricular ejection fraction(LVEF) were compared between the two groups 1 year after treatment.Results Compared with medicine therapy group,delayed PCI significantly increased LVEF and obviously decreased the mortality,recurrence of myocardial infarction and incidence of angina(P<0.05 or P<0.01).Conclusion Delayed PCI can improve the prognosis of AMI.更多还原