【摘要】 报告1例丘疹性红皮病。患者女,58岁。因躯干、双上肢伸侧及臀部红褐色丘疹伴瘙痒2年就诊。皮肤科检查:躯干、双上肢伸侧及臀部可见较多红褐色的扁平丘疹,表面少许鳞屑,有融合趋向,呈红皮病样损害。实验室检查:外周血淋巴细胞减少,血清IgE增高。皮损组织病理学检查:角化过度,棘层肥厚,表皮突细长下延,真皮浅层血管周围少量淋巴细胞浸润。皮损免疫组化:CD3、CD45RO、CD79a及KP-1阳性,CD20弱阳性,granzyme B及CD56阴性。诊断:丘疹性红皮病。更多还原

【Abstract】 A 58-year-old woman has a 2-year history of pruritic eruption.Clinically,flat topped,red-to-brown and coalescing papules were presented on the back,buttocks and the extensor aspect of the upper limbs.The lesions spared the axillary, inguinal regions and cubital fossae and skin folds on the abdomen and sub-mammary area,resulting in the typical ’deck-chair’ sign.The back showed a papular eruption following the Langer’s line.The abnormal laboratory findings were lymphopenia and an elevated semm IgE level.The skin histopathology evidenced the hyperkeratosis and acanthosis in the epidermis,and a small number lymphocyte infiltration around the blood vessel in the upper dermis.Immunohistochemisty showed the positive staining of CD3,CD45RO,CD79a,KP-1,weakly positive staining of CD20,and negative staining of granzyme B and CD56.The diagnosis of papuloerythroderma is made.更多还原