【摘要】 目的:分析体外授精/单精子卵胞浆内显微注射-胚胎移植(IVF/ICSI-ET)前解脲支原体(UU)和沙眼衣原体(CT)感染与妊娠结局的关系。探讨IVF/ICSI-ET前常规检测宫颈分泌物UU和CT的临床意义。方法:回顾性分析2008年1-12月首次在该中心行IVF/ICSI-ET,术前进行宫颈分泌物UU和CT检测的患者共1 802例,根据UU和CT检测结果,将患者分为UU和CT均阴性、UU阳性、CT阳性3组,比较各组间受精率、卵裂率、优质胚胎率、临床妊娠率、种植率、异位妊娠发生率和流产率有无差异以及CT或UU感染与不孕类型、是否存在盆腔因素病因、阴道清洁度、对移植操作的影响等关系。结果:不孕患者IVF/ICSI-ET治疗时UU感染患者的妊娠结局未受到影响.CT感染对妊娠结局有负面影响。结论:对于无症状的UU感染患者IVF术前不必要投入大量抗生素治疗,对于CT感染者建议治愈后进行胚胎移植。更多还原

【Abstract】 Objective:To observe the relationship between the infections of Ureaplasma urealyticum(UU) and Chlamydia trachomatis (CT) in cervical secretion and pregnancy consequences among women receiving in vifro fortilization-embryo trarsfer (IVF/ICSI-ET) and to investigate the predictive significance of cervical secretion test for UU and CT infection in women prior to the procedure.Methods:According to retrospective analysis,1802 patients receiving IVF/ICSI-ET in the center were collected from January 2008 to November 2008.They were divided into three groups:positive for UU,positive for CT and negative for UU and CT.Fertilization rate,cleavage rate,top quality embryo rate,implantation rate,clinical pregnancy rate,abortion rate and ectopic pregnancy rate in the three groups were compared.And the association was also analyzed between infertility type,pelvic infection,vagina sanitary grade,the impact on the transplant operation and outcomes of microbiological screening for UU and CT.Results:There was no relationship between UU infection and IVF/ICSI outcome.However,CT infection had been associated with adverse outcome.Conclusion:It is not necessary for asymptomatic UU infections to undergo a lot of antibiotic therapy before IVF/ICSI-ET attempt.However,for the patients with positive cervical secretion test for CT,it is important to treat the patients before the procedure.更多还原