【摘要】 目的筛选纵隔肿瘤患儿发生气道梗阻的术前危险因素。方法回顾性收集109例纵隔肿瘤患儿的术前临床和影像学资料,对14种待筛选的术前因素与气道梗阻的关系进行分析。结果 109例患儿中21例(19.3%)出现气道梗阻。单因素分析中,有无气道梗阻两组间年龄(P=0.004)、体重(P=0.017)、喘鸣(P=0.000)、端坐呼吸(P=0.013)、上腔静脉综合征(P=0.042)、位于前纵隔(P=0.000)、支气管受压(P=0.001)和气管横截面积百分比(cross sectional area,%CSA)(P=0.000)差异有统计学意义。Logistic回归分析中,气管%CSA与气道梗阻具有独立相关性(P=0.022)。经受试者工作特征曲线(receiver operating characteristic curve,ROC曲线)分析,气管%CSA的最佳截断点为50.5%。结论气管%CSA≤50.5%是纵隔肿瘤患儿发生气道梗阻的独立危险因素。更多还原

【Abstract】 Objective To identify the preoperative risk factors associated with airway obstruction in children with mediastinal masses.Methods The preoperative clinical and imaging datas of 109 children with mediastinal mass were collected retrospectively. The relationship between the 14 possible preoperative risk factors and airway obstruction were analysised.Results Twenty-one of one hundred nine(19.3%)patients experienced airway obstruction. For the univariate analysis, eight preoperative features were associated with airway obstruction:age(P=0.004),weight(P=0.017),stridor(P=0.000),orthopnea(P=0.013),superior vena cava syndrome(P=0.042),located in the anterior mediastinum(P=0.000),bronchial compression(P=0.001)and tracheal %cross sectional area(CSA) (P=0.000).For the logistic regression analysis, tracheal %CSA had a independent association with airway obstruction(P=0.022). The examination of receiver operating characteristic curve(ROC) showed that the cutpoint of tracheal %CSA was 50.5%.Conclusion The tracheal %CSA≤50.5% is the independent risk factors associated with airway obstruction.更多还原