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18F-FDG PET/CT显像在结直肠癌术前分期中的价值

The Diagnostic Value of 18F-FDG PET/CT Imaging in Preoperative Staging of Colorectal Cancer

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【作者】 王大龙于丽娟田墨涵任美丽张士德高波

【Author】 WANG Dalong,YU Lijuan,TIAN Mohan,et al. Department of Radiology,The Second Affiliated Hospital of Harbin Medical University,Harbin 150086,P.R.China

【机构】 哈尔滨医科大学附属第二医院放射线科哈尔滨医科大学附属第三医院PET/CT中心沈阳军区沈司第二干休所

【摘要】 目的探讨18F-FDG PET/CT在结直肠癌术前TNM分期中的应用价值。资料与方法 33例疑结直肠肿瘤患者均于手术治疗前行全身PET/CT扫描,将患者PET/CT检查结果与手术病理学检查结果进行比较分析。结果 PET/CT诊断结直肠癌原发灶的敏感性、准确性分别为100%和96.97%;PET/CT对术前结直肠癌侵犯局部浆膜、淋巴结转移、远处转移及TNM分期的准确性分别为75.00%、78.12%、96.87%和71.87%,经Kappa一致性检验,PET/CT上述诊断结果与手术病理学检查结果具有较好的一致性(0.429,0.559,0.920,0.619,P均<0.05)。结论结直肠癌18F-FDG PET/CT术前检查,是结直肠癌的术前临床分期中有效的影像学评价手段。

【Abstract】 Objective To evaluate the value of 18F-FDG PET/CT on the TNM staging of colorectal cancer before surgery.Materials and Methods 33 patients with colorectal tumor received 18F-FDG PET/CT before surgery.PET/CT findings were compared with pathological results and statistical analysis were performed.Results The sensitivity,accuracy of diagnosing primary colorectal lesions was 100%,96.97% respectively by PET/CT.The diagnostic accuracy of local chorion invasion and Lymph node metastasis and distant metastasis and TNM stage before operation in colorectal cancer were 75.00%,78.12%,96.87%,71.87% respectively,and the correlation with pathological results were 0.429,0.559,0.920,0.619,respectively(P<0.05).Kappa coefficients showed that the correlation between manifestations on PET/CT and operative pathology were good.Conclusion PET/CT is an effective diagnostic imaging method in evaluating the staging of colorectal carcinomas before surgery.

【关键词】 结直肠癌分期PET/CT
【Key words】 Colorectal cancer Staging PET/CT
【基金】 黑龙江省自然科学基金资助项目(编号:D200863);哈尔滨市科技创新人才研究专项资金项目(2011RFXYS061)
  • 【文献出处】 临床放射学杂志 ,Journal of Clinical Radiology , 编辑部邮箱 ,2012年01期
  • 【分类号】R735.3
  • 【被引频次】41
  • 【下载频次】458
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