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50例鼻咽结核的诊治分析

Pathogeny and treatment of 50 nasopharyngeal tuberculosis cases

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【作者】 简奕娈刘宝瑛郭丽霞孔少颜苏肖敏卢春丽

【Author】 JIAN Yiluan LIU Baoying GUO Lixia KONG Shaoyan SU Xiaomin LU Chunli(Department of Otolaryngology,Guangzhou Chest Hospital,Guangzhou,510095,China)

【机构】 广州市胸科医院五官科

【摘要】 目的:分析鼻咽结核的临床表现及诊疗特点,为提高鼻咽结核的临床诊断率提供科学依据。方法:回顾性分析在广州市胸科医院就诊并确诊为鼻咽结核的50例患者的临床资料。50例患者均采用3HRZS(E)/9HR(E)方案抗结核治疗1年,局部用异烟肼、利福平、链霉素的针剂联合喷鼻3个月。结果:全部患者治疗期间没有出现耐药现象,全部完成1年的疗程后治愈并在停药后随访2年均无复发。结论:鼻咽结核较少见,临床表现不典型,极易误诊,充分了解发病的成因及发病初期鼻咽镜下的临床表现及特点,并及时做活检组织病理检查是诊断的关键,从而明确诊断并给予正规的抗结核治疗。

【Abstract】 Objective:To analyze the clinical characters and treatment of nasopharyngeal tuberculosis,and to provide a scientific basis for improving clinical diagnosis of nasopharyngeal tuberculosis.Method: The clinical materials of 50 patients diagnosed as nasopharyngeal tuberculosis in Guangzhou Chest Hospital were reviewed and analyzed.All the 50 patients were given regular antituberculosis treatment with 3HRZS(E)/9HR(E) for one year,and were treated through nasal spray with combination medication of isoniazid,rifampicin and streptomycin injection solution for 3 months.Result:All patients were cured through regular antituberculosis treatment for one year,and no recrudescence cases were found in 2 years of follow-up.Conclusion:Nasopharyngeal tuberculosis is rare and the clinical manifestation is atypical.It is extremely easy to cause clinical misdiagnosis.A full understanding of the pathogenesis,timely clinical characters under nasopharyngoscope and histopathological examination results are the keys to diagnosis,and to giving regular antituberculosis treatment to obtain satisfactory curative effect.

【关键词】 结核鼻咽诊断治疗
【Key words】 tuberculosisnasopharynxdiagnosistherapy
  • 【文献出处】 临床耳鼻咽喉头颈外科杂志 ,Journal of Clinical Otorhinolaryngology Head and Neck Surgery , 编辑部邮箱 ,2012年24期
  • 【分类号】R529.8
  • 【被引频次】9
  • 【下载频次】129
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