【摘要】 目的探讨高敏C反应蛋白、游离脂肪酸在心房颤动(房颤)发病中的意义。方法测定41例持续性房颤患者(持续性房颤组)、42例阵发性房颤患者(阵发性发颤组)以及39例健康体检者(正常对照组)血清中高敏C反应蛋白及游离脂肪酸水平。结果血清高敏C反应蛋白及游离脂肪酸水平在持续性房颤组、阵发性房颤组均显著高于对照组(P<0.01),且持续性房颤组高于阵发性房颤组(P<0.01),各组间差异均有统计学意义。结论高敏C反应蛋白及游离脂肪酸增高所反映的炎症状态和代谢紊乱可能促进房颤的发生发展。更多还原

【Abstract】 Aim To evaluate the clinical applicability of high sensitivity-C reactive protein(hs-CRP)and free fatty acid(FFA) in atrial fibrillation(AF). Methods The 122 cases were divided into 3 groups as 41 persistant AF,42 paroxysmal AF,and 39 healthy volunteers;the serum levels of hs-CRP and FFA were detected. Results The levels of hs-CRP and FFA in patients of persistant AF and paroxysmal AF were significantly higher than those in the control group(P<0.01).And the above levels in persistant AF were significantly higher than those in paroxysmal AF(P<0.01). Conclusion The increase of hs-CRP and FFA indicate inflammation and abnormal metabolism might promote the occurrence and development of AF.更多还原