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茶树根的抗炎镇痛作用研究

Research on the Anti-inflammatory and Analgesic Actions of Tea Plant Root

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【作者】 余雄英周军陈美兰欧阳永伟罗小泉

【Author】 YU Xiong-ying 1,ZHOU Jun1,CHEN Mei-lan2,OU YANG Yong-wei1,LUO Xiao-quan1(1.Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;2.Pharmaceutical Research Institute of China Academy of Traditional Chinese Medicine,Beijing 100700,China)

【机构】 江西中医学院北京中医研究院中药研究所

【摘要】 目的探讨茶树根的抗炎、镇痛作用。方法采用二甲苯致小鼠耳廓炎症,左右耳重差(肿胀度)的影响,观察茶树根的抗炎作用;采用对小鼠热板法致痛和醋酸致小鼠扭体反应的方法,观察茶树根的镇痛作用。结果茶树根可使小鼠耳廓肿胀度明显减小,同时使小鼠扭体反应次数明显减少(与对照组比较P<0.05或P<0.01);高剂量茶树根水煎剂能明显延长小鼠舔后足的的潜伏期(P<0.01)。结论茶树根具有明显的抗炎镇痛作用。

【Abstract】 Objective To study the anti-inflammatory and analgesic effects of tea plant roots.Methods The experiment of anti-inflammatory effects of tea plant roots were studied by mouse’s auricular swelling caused by dimethylbenzene.The experiments of the analgesic effects of tea plant roots were studied by hot-plate test and acetic acid-induced wringing test in mice.Results Tea plant roots could not only reduce the auricular swelling of mices remarkably,but also inhibit acetic acid-induced wringing reaction of mices(P<0.05 or P<0.01).Meanwhile,high dose of tea plant roots could prolong the latency time of mice licking their back feet remarkably(P<0.01).Conclusion Tea plant roots showed strong anti-inflammatory and analgesic effects.

【关键词】 茶树根抗炎镇痛
【Key words】 tea plant rootanti-inflammatory effectanalgesic effecteffect.
【基金】 2010年度江西省“十一五”重点学科青年教师培养计划资助项目(098506)
  • 【文献出处】 现代中药研究与实践 ,Research and Practice on Chinese Medicines , 编辑部邮箱 ,2012年04期
  • 【分类号】R285.5
  • 【被引频次】5
  • 【下载频次】217
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