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冠心病患者超敏C反应蛋白及总胆红素检测的临床意义

Clinical significance of serum total bilirubin and Hs-CRP in patients with coronary heart disease

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【作者】 钟志娟许坚锋陈红涛李冬梅郭国威

【Author】 ZHONG Zhi-juan,XU Jian-feng,CHEN Hong-tao△,LI Dong-mei,GUO Guo-wei(Department of Clinical Laboratory,Fifth Affiliated Hospital,Sun Yat-sen University,Zhuhai,Guangdong 519000,China)

【机构】 中山大学附属第五医院检验科

【摘要】 目的探讨冠心病(CHD)患者血清总胆红素及超敏C反应蛋白(hs-CRP)测定的临床意义。方法 60例冠心病患者及健康对照60例,用钒酸盐氧化法测定总胆红素,用透射比浊法测定hs-CRP浓度并做结果分析。结果冠心病患者血清总胆红素水平与健康对照组相比降低(P<0.05),hs-CRP水平与健康对照组相比增高(P<0.01)。结论血清总胆红素与冠心病的发生率呈负相关;血清C-反应蛋白与冠心病的发生率呈正相关。

【Abstract】 Objective To investigate the clinical significance of serum total bilirubin and high sensitivity C-reactive protein(hs-CRP) in the patients with coronary heart disease(CHD).Methods The serum levels of total bilirubin and hs-CRP were respectively determined by the vanadium-acid oxidation method and the transmission turbidimetry in 60 cases of CHD(CHD group) and 60 healthy individuals(control group).Results The serum level of total bilirubin in the CHD group was decreased as compared with the healthy group(P<0.05),while the serum level of Hs-CRP was increased as compared with the healthy group(P<0.001).Conclusion There is negative correlation between serum total bilirubin level and the occurrence of CHD.There is positive correlation between hs-CRP and the occurrence of CHD.

  • 【文献出处】 检验医学与临床 ,Laboratory Medicine and Clinic , 编辑部邮箱 ,2012年20期
  • 【分类号】R541.4
  • 【被引频次】13
  • 【下载频次】89
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