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妊娠高血压综合征孕妇血清胱抑素C水平变化病例对照研究

Case-control study on serum cystatin C level in gravidas with pregnancy induced hypertension syndrome

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【作者】 莫伟林还珠钟毓琼梁仪

【Author】 MO Wei1,LIN Huan-zhu2,ZHONG Yu-qiong1,LIANG Yi1(Second Affiliated Hospital,Guangdong Medical College:1.Department of Laboratory;2.Department of Obstetrics and Gynecology,Zhanjiang,Guangdong 524003,China)

【机构】 广东医学院第二附属医院检验科广东医学院第二附属医院妇产科

【摘要】 目的探讨妊娠高血压综合征孕妇血清胱抑素C水平变化及其临床价值。方法利用全自动生化仪测定56例健康妊娠晚期妇女和60例妊娠高血压综合征孕妇血清胱抑素C水平和其他肾功能指标。结果妊娠高血压综合征孕妇血清胱抑素C水平较健康晚期孕妇明显增高(P<0.01)。结论血清胱抑素C在重度妊高征孕妇中有明显变化,能反映妊高征者早期肾损害,同时反映病情发展。

【Abstract】 Objective To explore the changes and clinical value of cystatin C level in gravidas with pregnancy induced hypertension syndrome(PIH).Methods The cystatin C level and other kidney function indexes were detected by the automatic biochemical analyzer in 56 healthy gravidas of late pregnancy and 60 gravidas with PIH.Results The cystatin C level in PIH gravidas was increased significantly compared to the healthy gravidas of late pregnancy(P<0.01).Conclusion The cystatin C level in severe PIV gravidas has significant change,which reflects the early renal damage in PIH as well as the progress of the disease condition.

【关键词】 妊娠高血压胱抑素
【Key words】 pregnancyhypertensioncystatin
  • 【文献出处】 检验医学与临床 ,Laboratory Medicine and Clinic , 编辑部邮箱 ,2012年19期
  • 【分类号】R446.6;R714.246
  • 【被引频次】12
  • 【下载频次】84
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