【摘要】 实验以甲醇与1-萘乙酸先预酯化,再将预酯化液在262-磺化分子筛固定床反应器中高温酯化工艺合成1-萘乙酸甲酯。考察了高温酯化反应的影响因素。最佳高温酯化条件为:预酯化液的酸值(KOH)为60mg/g,甲醇与1-萘乙酸的质量比为0.5,反应温度为95℃,反应物流量为0.9mL/min,总酯化率达99.0%以上。催化剂循环使用11次,表现出优良的催化活性和稳定性。与传统工艺相比无需中和、水洗、萃取等步骤便可得到高纯度的产品。更多还原

【Abstract】 Esterification of 1-naphthylacetic acid with methanol was carried out first.Then such fore-esterification liquid was used as raw materials for the synthesis of methyl 1-naphthylacetate by high temperature esterification catalyzed by 262-sulfonated molecular sieve in fixed bed reactor.Factors affecting the high temperature esterification were investigated.The optimum conditions were found as follows: mass ratio of methyl alcohol to 1-naphthylacetic acid 0.5,flow rate of reactant 0.9 mL/min,reaction temperature 95 ℃,reaction time 1 h.Under the optimum conditions,the esterification yield could reach above 99%.The catalysts were reused for 11 times with 99% of the esterification yield,demonstrating the high catalytic performance and stability of the catalysts.Compared with the traditional process,this method produces high purity methyl 1-naphthylacetate without the tedious steps like neutralization,washing,extraction and so on.更多还原