【摘要】 目的探讨肝动脉化疗栓塞(TACE)联合CT引导射频消融(RFA)序贯治疗原发性中小肝癌的临床应用。方法对59例肝细胞性中小肝癌患者实施TACE联合CT引导RFA序贯治疗。结果 59例患者初次治疗,共80枚病灶,行TACE和RFA序贯治疗技术成功率100%。术后随访6～24个月,21例患者有病灶残余,再次行RFA或序贯治疗,3例再次联合放射性125I粒子植入治疗后,病灶控制良好。并发症有胆汁瘤合并胆道感染1例、门静脉分支血栓1例。结论 TACE联合CT引导RFA序贯治疗中小肝癌是一种微创、有效的方法,同时注意手术操作细节,对提高手术成功率,降低手术并发症有重要意义。更多还原

【Abstract】 Objective To investigate the clinical application of sequential therapy with transarterial chemoembolization(TACE) and CT-guided radiofrequency ablation(RFA) in treating small or moderate sized hepatocellular carcinoma(HCC).Methods A total of 59 patients with small or moderate sized HCC received sequential TACE and CT-guided RFA.The technical and clinical results were analyzed.Results A total of 80 hepatic lesions were detected in 59 patients.The technical success rate of sequential treatment with TACE and CT-guided RFA was 100%.Patients were followed up for 6-24 months.CT-guided RFA or sequential treatment was repeated in 21 patients because of residual lesions.Additional 125I seed implantation was carried out in three patients,and the lesions were well controlled.Complications included biloma complicated by bile duct infection(n = 1) and portal vein branch thrombosis(n = 1).Conclusion The sequential treatment with TACE and CT-guided RFA is an effective and mini-invasive therapeutic option for small or moderate sized HCC.更多还原