【摘要】 目的探讨染色体多态性与男性不育的关系。方法对297例临床诊断为少精子症、无精子症的男性不育患者按常规技术方法制备外周血染色体,并对染色体核型进行分析。结果 297例患者中有68例染色体核型异常,异常检出率为22.90%。其中,多态性变异12例,占异常核型的17.65%,包括次缢痕增长3例,9号染色体倒位2例,D/G组随体变异1例,Y染色体变异6例。结论染色体多态性与男性不育存在明显关系,不能忽视其临床效应。更多还原

【Abstract】 Objective To explore the relationship between chromosomal polymorphism and male infertility.Methods Chromosome in peripheral blood from 297 oligospermia or azoospermia infertility patients were cultured and stained by G banding.Chromosomal karyotype of 297 cases were analyzed.Results The results showed abnormal karyotype in 68 cases among 297 oligospermia and azoospermia patients accounting for 22.89% in all subjects.Chromosomal polymorphism was 12 cases accounting for 17.65% in chromosome abnormalities.Among abnormalities,secondary constriction increasing were 3 cases,inversion of the ninth chromosomes were 2 cases,D/G set with body variant was 1 case and Y chromosome variation were 6 cases.Conclusion Chromosomal polymorphism is the main reason for male infertility so that the clinical effects can’t be ignored.更多还原