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骨关节炎影响因素的1:1配对病例对照研究

A 1:1 matched case-control study on influential factors of osteoarthritis

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【作者】 郭立燕张雪文翟敏卫宏图张磊常志任

【Author】 GUO Li-yan1,ZHANG Xue-wen1,ZHAI Min1,WEI Hong-tu2,ZHANG Lei3,CHANG Zhi-ren1.1.Department of Epidemiology,Jining Medical University,Jining 272067,China;2.Department of Orthopaedics,No.1 People’s Hospital of Jining,Jining 272111,China;3.Department of Surgery Pandect,Jining Medical University,Jining 272067,China

【机构】 济宁医学院流行病学教研室济宁市第一人民医院骨外科济宁医学院外科总论教研室

【摘要】 目的研究骨关节炎发病的影响因素,为骨关节炎的预防控制提供科学依据。方法应用1∶1配对病例对照研究方法,从济宁市及兖州的4所医院调查108例骨关节炎患者,以性别相同、年龄相近(±2岁以内)作为配对条件选择对照108例,收集相关的资料进行单因素、多因素条件Logistic回归分析。结果体质指数、饮酒和关节外伤史均与骨关节炎呈正相关,OR(95%CI)分别为2.62(1.11~6.19),11.88(2.27~62.14),15.41(2.05~115.96),日照、食用豆制品、新鲜蔬菜和水果是骨关节炎的保护因素,OR(95%CI)分别为0.30(0.13~0.69)、0.10(0.02~0.47)、0.07(0.02~0.30)和0.35(0.13~0.98)。结论肥胖、饮酒和关节外伤史均为骨关节炎的危险因素,多摄入新鲜蔬菜、新鲜水果、豆制品、多晒太阳则是骨关节炎的保护性因素。

【Abstract】 Objective To study the influential factors of osteoarthritis in the population.Methods A 1∶1 matched case-control study was conducted.108 of patients with osteoarthritis were investigated from four hospitals of Jining and Yanzhou.108 controls who did not suffer from osteoarthritis were also investigated.The case and control matching factors were the same sex,age difference less than 2 years.The data were analyzed by the single-factor and multi-factor conditional logistic regression.Results Body mass index,history of drinking alcohol and joint trauma were positively correlated with osteoarthritis,ORs(95%CI) were 2.62(1.11-6.19),11.88(2.27-62.14) and 15.41(2.05-115.96),respectively.Exposure in sun-ray,edible bean products,fresh vegetables and fresh fruits could reduce the incidence of osteoarthritis,which were negatively correlated with osteoarthritis,ORs(95%CI) were 0.30(0.13-0.69),0.10(0.02-0.47),0.07(0.02-0.30),0.35(0.13-0.98),respectively.Conclusions Obesity,alcohol and injury history are the risk factors of osteoarthritis.More intakes of fresh vegetables,fresh fruits,soy products,and duration of exposure in the sun are the protective factors of osteoarthritis.

  • 【文献出处】 中华疾病控制杂志 ,Chinese Journal of Disease Control & Prevention , 编辑部邮箱 ,2012年08期
  • 【分类号】R181.24
  • 【被引频次】11
  • 【下载频次】467
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