【摘要】 目的明确心脏移植术后患者冠状动脉病变及其对患者长期存活的影响。方法对1992年4月至2000年4月在哈尔滨医科大学附属第二医院接受心脏移植超过10年的4例患者进行了回顾性分析。结果 4例患者都发生不同程度的移植物血管病变,且10年后4例患者心脏射血分数(EF)全部﹥50%并心功能良好。其中1例存活时间超过了18年,是中国心脏移植术后存活时间最长的,也是亚洲现存心脏移植术后存活时间最长的。结论心脏移植术后长期存活并维持其供体心脏的正常的血流动力学功能是可能的,术后移植物血管病变是同种异体心脏移植术后的常见并发症,积极地预防有利于心脏移植患者的长期存活。更多还原

【Abstract】 Objective To analyse the influence of the transplant vasculopathy after heart transplantation on long-term survival patients.Methods We analyzed clinical outcomes in the group of 4 patients(>10 years)who have undergone heart transplantation at The Second Affiliated Hospital of Harbin Medical University from April 1992 to April 2000.Results There was different degree of transplant vasculopathy in the long-term survival patients.Their left ventricular ejection fractions were more than fifty percent and cardiac function kept well.The longest survival patients was more than 18 years after transplantation who was the longest one in China and was the longest heart transplantation patient alive in Asia.Conclusion Long-term survivors could maintain normal hemodynamic function of their allografts and enable long-term survival after cardiac transplantation.Transplant vasculopathy are more common after transplantation.Aggressive preventive and therapeutic measures are essential to limit the risk factors for development of complications.更多还原