【摘要】 乙氧基苯是一种重要的有机合成中间体,应用于农药、染料、化学试剂,药品如非那西丁、氢化可的松、醋酸泼尼松等的合成,本文研究了利用相转移催化反应在不同的催化剂反应条件下,合成中间体乙氧基苯,在氢氧化钠存在下,苯酚与硫酸二乙酯于60-65℃反应3h条件下合成乙氧基苯,产品产率达90%以上。对不同的催化剂的使用和反应时间进行了条件优化,对产品乙氧基苯的IR谱图、NMR谱图进行了确认和详细的分析.更多还原

【Abstract】 Ethoxybenzene is an important organic chemical intermediate.It is applied widely in synthesis of pesticide,dye,chemical reagents,and drugs such as acetophenetidin,hydrogen cortisone and acetate prednisone.In this research we used different catalysts to synthesize ethoxybenzene by phase transfer catalytic method.Ethoxybenzene was synthesized using phenol and diethyl sulfate in toluene in the presence of sodium hydrate,by using different phase transfer catalysts.The product’s yield was over 90%under the reaction temperature of 60 ℃ and the reaction time of 3.0h.The different catalysts usages and reaction times were optimized and discussed,and the product’s IR spectra,NMR spectra had been characterized and discussed in detail.更多还原