【摘要】 目的观察前列地尔(曼新妥)治疗穿支动脉梗死的临床疗效。方法选择穿支动脉梗死患者70例,分为治疗组35例和对照组35例,对照组给予胞二磷胆碱、肠溶阿司匹林、他汀类降脂药、降压、降糖、康复等治疗;治疗组在对照组治疗的基础上,加用前列地尔射液10μg+生理盐水10mL静脉推注,1次/d,疗程14d。结果治疗组神经功能缺损评分下降明显,与对照组相比差异有统计学意义(P<0.05)。结论前列地尔(曼新妥)治疗穿支动脉梗死疗效显著,可改善穿支动脉梗死患者的预后。更多还原

【Abstract】 Objective To observe the clinical efficacy of alprostadil(Manxintuo) in the treatment of penetrating artery cerebral infarction.Methods Seventy patients with penetrating artery cerebral infarction were selected,and were randomly divided into two groups,35 patients in therapy group and 35 patients in control group.The control group was given citicoline,aspirin,statin lipid-lowering drugs,lowering blood pressure,hypoglycemic,rehabilitation therapy and so on.The therapy group was injected with Manxintuo(+NS 10 mL)once everyday for 14 days on the basis of control group.Results There was significant difference between the therapy group and control group in neurologic impairment score change(P<0.05).Conclusion Alprostadil has a significant effect in the treatment of penetrating artery cerebral infarction.It can improve the prognosis of penetrating artery cerebral infarction.更多还原