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丹参川芎嗪注射液配置后放置时间对静脉炎发生率的影响

Influence of standing time after preparation of salvia ligustrazine injection on the incidence of phlebitis

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【作者】 刘平刘元

【Author】 LIU Ping1,LIU Yuan2 1.Department of Cardiology,People’s Hospital of Wuhan University,Wuhan 430060,China;2.Department of Cardiology,People’s Hospital of Zhuhai,Zhuhai 519000,China

【机构】 武汉大学人民医院心血管内科珠海市人民医院血管内科

【摘要】 目的探讨丹参川芎嗪注射液配置后放置不同时间静脉滴入对静脉炎发生率的影响。方法将180例冠心病患者随机分为A、B、C 3组(每组各60例)。3组患者均使用丹参川芎嗪20 ml+木糖醇注射液250 ml以40滴/min的滴速进行静脉滴入。A组药液配置后立即滴入,B组药液配置后放置30 min滴入,C组药液配置后放置1 h滴入,观察3组患者静脉炎的发生情况。结果丹参川芎嗪注射液配置1 h后进行静脉滴入时静脉炎的发生率明显高于其他两组(P<0.05),而丹参川芎嗪注射液配置后立即滴入与30 min内静脉滴入静脉炎的发生率比较,差异无统计学意义(P>0.05)。结论丹参川芎嗪注射液配置后放置30 min以内进行静脉滴入可减少静脉炎的发生,为临床安全用药提供参考。

【Abstract】 Objective To explore the impact of standing time after preparation of salvia ligustrazine injection on the incidence of phlebitis.Methods A total of 180 cases of coronary heart disease patients were randomly divided into three groups(60 cases in each group).Three groups of patients received injection of 20 ml salvia ligustrazine and 250 ml liquid xylitol with 40 drops per min.Group A adopted immediate injection after preparation.Group B received injection 30 minutes after preparation.Group C received injection 1 hour after prepartion.The incidence of phlebitis was observed.Results The incidence rate of phlebitis in Group C was significantly higher than Group A and B(P<0.05),and the difference between Group A and B was not significant(P>0.05).Conclusion The salvia ligustrazine injection should be used within 30 minutes after preparation,which can reduce the incidence of phlebitis,so as to provide reference for clinical medication safty.

【基金】 武汉大学人民医院院内临床研究课题(HX0005)
  • 【文献出处】 护理管理杂志 ,Journal of Nursing Administration , 编辑部邮箱 ,2012年08期
  • 【分类号】R472
  • 【被引频次】10
  • 【下载频次】124
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