【摘要】 分析了阿坝地区的岩石、饮用水、农作物及其根系土中硒的不同存在形态的分布,并结合生物有效性深入研究了硒元素分布与大骨节病病因的联系和调控机理.阿坝地区的环境(岩石、土壤、水)中全硒浓度、农作物中硒的富集系数和水溶性硒占总硒的含量均远低于非病区;硒在氧化还原条件(Eh平均值143.27 mV)和酸碱度(pH 6.51—8.48)的控制下主要以亚硒酸态的稳定形式存在.元素铝、铁等的富集可能会促进硒的沉淀和络合,制约硒的生物有效利用率,进而导致人体硒摄入不足,最终激发人类微小病毒B19(HPV B19)的毒性,引发大骨节病.通过采取土壤增施硒肥、改善水质、改变膳食结构等方法可以有效地提高环境中硒的水平及其生物有效性,以缓解大骨节病的病情及发病率.更多还原

【Abstract】 The distribution of selenium species in rocks,drinking water,crops,cultivated soils and their relevant bioavailabitity in Aba,Sichuan were investigated.In Aba area,total selenium concentration in the environment(including rocks,soils and water),selenium enrichment coefficient in the crops,and the percentage of water-soluble to total Se were all much lower than those in disease-free areas.Selenite was found to be the most stable species when oxidation-reduction potential(Ehmean=143.27 mV) and acidity(pH 6.51—8.48) were controlled.Accumulation of Al,Fe and other elements might enhance the precipitation and complexation of Se,reduce the bioavailability of Se,and result in selenium deficiency in humans.Consequently,the toxicity of B19(HPV B19) might be stimulated which could induce the Kaschin-Beck disease(KBD).Therefore,KBD can be prevented by increasing the selenium levels and its bioavailabitity with various methods,such as fertilizing soils with selenate,improving drinking water quality,ameliorating dietary structure.更多还原