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盐酸法舒地尔治疗急性脑梗死47例疗效观察
Observation of curative effect of Fasudil hydrochloride on acute cerebral infarction
【摘要】 目的观察盐酸法舒地尔治疗急性脑梗死的临床疗效。方法将92例急性脑梗死患者随机分为2组。治疗组47例在常规治疗基础上加用盐酸法舒地尔注射液,对照组45例在常规治疗基础上加用丹红注射液。2组均14 d为1个疗程,1个疗程后观察2组神经功能缺损评分(NDS)和临床疗效。结果治疗组治疗后NDS明显改善(P<0.05),与对照组比较差异有统计学意义(P<0.05);治疗组总有效率78.72%,对照组总有效率55.56%,2组比较差异有统计学意义(P<0.05)。结论盐酸法舒地尔可以改善急性脑梗死患者的神经功能缺损,提高疗效。
【Abstract】 Objective To observe the curative effect of Fasudil hydrochloride on acute cerebral infarction.Methods 92 cases of acute cerebral infarction were randomly divided into two groups.Treatment group(n=47) received combination of routine therapy and Fasudil hydrochloride.Control group(n=45) received combination of routine therapy and Danhong injection.The course was 14 days in two groups.Neurologic Deficit Scale(NDS) and clinical effect were observed after a course.Results The NDS in treatment group was significantly improved after treatment.There was significant difference between two groups(P<0.05).The total effective rate in treatment group(78.72%) was higher than that in control group(55.56%,P<0.05).Conclusion Fasudil hydrochloride can improve neurological impairment of patients with acute cerebral infarction,and increase curative effect.
【Key words】 Acute cerebral infarction; Analogue; Derivative; Vasodilator;
- 【文献出处】 河北中医 ,Hebei Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2012年03期
- 【分类号】R743.33
- 【被引频次】2
- 【下载频次】55