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盐酸法舒地尔治疗急性脑梗死47例疗效观察

Observation of curative effect of Fasudil hydrochloride on acute cerebral infarction

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【作者】 张力赵立杰王晓鹏李敏娟赵卓华魏建华

【Author】 ZHANG Li*,ZHAO Lijie,WANG Xiaopeng,et al. *The Third Department of Internal Medicine,Zhao County People’s Hospital,Hebei,Zhao County 051530

【机构】 河北省赵县人民医院内三科河北医科大学第二医院神经内科

【摘要】 目的观察盐酸法舒地尔治疗急性脑梗死的临床疗效。方法将92例急性脑梗死患者随机分为2组。治疗组47例在常规治疗基础上加用盐酸法舒地尔注射液,对照组45例在常规治疗基础上加用丹红注射液。2组均14 d为1个疗程,1个疗程后观察2组神经功能缺损评分(NDS)和临床疗效。结果治疗组治疗后NDS明显改善(P<0.05),与对照组比较差异有统计学意义(P<0.05);治疗组总有效率78.72%,对照组总有效率55.56%,2组比较差异有统计学意义(P<0.05)。结论盐酸法舒地尔可以改善急性脑梗死患者的神经功能缺损,提高疗效。

【Abstract】 Objective To observe the curative effect of Fasudil hydrochloride on acute cerebral infarction.Methods 92 cases of acute cerebral infarction were randomly divided into two groups.Treatment group(n=47) received combination of routine therapy and Fasudil hydrochloride.Control group(n=45) received combination of routine therapy and Danhong injection.The course was 14 days in two groups.Neurologic Deficit Scale(NDS) and clinical effect were observed after a course.Results The NDS in treatment group was significantly improved after treatment.There was significant difference between two groups(P<0.05).The total effective rate in treatment group(78.72%) was higher than that in control group(55.56%,P<0.05).Conclusion Fasudil hydrochloride can improve neurological impairment of patients with acute cerebral infarction,and increase curative effect.

  • 【文献出处】 河北中医 ,Hebei Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2012年03期
  • 【分类号】R743.33
  • 【被引频次】2
  • 【下载频次】55
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