【摘要】 目的探讨脑尿钠肽联合其他血清指标的检测在超高龄住院患者心力衰竭诊断中的价值。方法回顾性分析2009年1月至2011年9月以心力衰竭住院治疗的89例高龄(≥80岁)患者的临床资料,包括脑尿钠肽、超敏C-反应蛋白、肌钙蛋白I、血清肌酐和心室射血分数值。结果 89例超高龄(≥80岁)住院患者中,脑尿钠肽>500pg/ml的有89例,脑尿钠肽>500pg/ml、超敏C-反应蛋白>5mg/L、肌钙蛋白I>0.1ng/ml、血清肌酐>97μmol/L的患者有76例,69例患者的射血分数值<40%,以脑尿钠肽>500pg/ml、超敏C-反应蛋白>5mg/L、肌钙蛋白I>0.1ng/ml、血清肌酐>97μmol/L联合检测诊断心力衰竭的特异性(90.79%)与以脑尿钠肽值>500pg/ml为依据诊断心力衰竭异性(85.39%)组间比较差异有统计学意义(P<0.05)。结论超高龄(≥80岁)住院患者心力衰竭发生率高且症状隐匿,联合检测脑尿钠肽、超敏C-反应蛋白、肌钙蛋白I、血清肌酐较单独脑尿钠肽检测诊断心力衰竭的可靠性和准确性高。更多还原

【Abstract】 Objective To explore the diagnosis value of combined detection of brain natriuretic peptide with the other serum markers for heart failure in advanced age patients (≥80 years).Methods The clinical data of 89 inpatients with heart failure whose age was ≥80 years from January to September in 2011 were retrospectively analyzed,and these parameters included BNP,hsCRP,TNI,Cr and EF.Results Among the 89 patients,89 patients had high BNP levels (BNP>500pg/ml),there were 76 patients with hs-CRP (>5mg/L),TNI (>0.1ng/ml),Cr (>97 μmol/L),and there were 69 patients with EF<40%.There was a significant difference in the diagnostic specificity for heart failure between combined detection group and simple BNP detection group (90.79% vs 85.39%,P<0.05).Conclusion The advanced age patients have higher incidence of heart failure,with insidious syndrome,and combined detection of BNP,hs-CRP,TNI,Cr is superior to simple BNP detection in the reliability and accuracy in diagnosing heart failure of advanced age patients.更多还原