【摘要】 目的探讨肌钙蛋白I(cTnI)、超敏C-反应蛋白(hs-CRP)及同型半胱氨酸(Hcy)联合检测对冠心病患者预后的预测价值。方法选择90例冠心病住院患者为观察组,选择同期体检的60例健康者为对照组。观察组患者出院后随访1个月,其中住院及随访期间发生心血管事件者26例,无事件者64例。比较对照组与观察组患者血清cTnI、hs-CRP及Hcy的差别。结果观察组患者血清cTnI、hs-CRP及Hcy水平显著高于对照组(P<0.01);观察组患者中有事件者血清cTnI、hs-CRP及Hcy水平显著高于无事件者(P<0.01),Pearson相关分析结果显示:三者为心血管事件的独立相关因素。结论 cTnI、hs-CRP及Hcy联合检测有助于提高冠心病患者的诊断,对评估预后具有重要意义。更多还原

【Abstract】 Objective To explore the value of joint detection of troponin I(cTnI),high-sensitivity c-reactive protein(hs-CRP) and homocysteine(Hcy) in the prognosis of coronary heart disease.Methods Ninety patients of coronary heart disease were selected as the study group and 60 healthy individuals as the control group.Patents in the study group were followed up for 1 month after discharge,and 26 patients were found having cardiovascular events,while 64 not.The levels of serum cTnI,hs-CRP and Hcy were compared between the two groups.Results The levels of serum cTnI,hs-CRP and Hcy in the study group were significantly higher than those in the control group(P<0.01);In the study group,the levels of serum cTnI,hs-CRP and Hcy were significantly higher in patients with cardiovascular events,compared with those not(P<0.01);Pearson correlation analysis showed that cTnI,hs-CRP and Hcy were independent risk factors of cardiovascular events.Conclusion Joint detection of cTnI,hs-CRP and Hcy is helpful for the diagnosis of coronary heart disease,which is of great significance for the evaluation of prognosis.更多还原