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超早期与早期微创穿刺治疗高血压性脑出血的比较

Comparison on ultra-early and early stage minimally invasive neurosurgery for hypertensive intracerebral hemorrhage

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【作者】 赖余柱杨建雄林立超郑达理叶志其

【Author】 LAI Yu-zhu,YANG Jian-xiong,LIN Li-chao,ZHENG Da-li,YE Zhi-qi (Department of Neurosurgery,Heyuan People’s Hospital,Guangdong,517000,China)

【机构】 广东省河源市人民医院神经外科

【摘要】 目的:探讨微创穿刺治疗幕上高血压脑出血(HICH)的手术时机与疗效。方法:回顾性分析2008年3月至2011年3月广东省河源市人民医院收治的92例血肿量为30~60 mL的幕上HICH患者的临床资料,患者均行微创穿刺配合尿激酶液化引流术,根据发病至治疗时间不同分为A组44例(脑出血时间≤6 h)和B组48例(脑出血时间6~24 h),比较两组患者的再出血率、病死率和痊愈率。结果:两组患者再出血率、病死率比较,差别无统计学意义(P>0.05);A组患者的痊愈率为85.4%,高于B组的65.2%(P<0.05)。结论:超早期微创穿刺配合尿激酶液化引流术治疗血肿量为30~60 mL的幕上HICH安全、有效。

【Abstract】 Objective:To explore the time for initiation and efficacy of minimally invasive neurosurgery for supratentorial hypertensive intracerebral hemorrhage(HICH).Methods:We did a retrospective analysis on the clinical profiles of 92 patients with supratentorial HICH(30-60 ml) admitted to Heyuan People’s Hospital between March 2008 and March 2011.All patients were treated with minimally invasive neurosurgery in combination with urokinase liquefied drainage and were assigned to group A(n = 44,≤6 hrs) and group B(n =48,6-24 hrs),based on the duration from disease onset to treatment intervention.The incidence of recurrent hemorrhage,mortality and rate of recovery were compared.Results:Both groups did not differ statistically in the incidence of recurrent hemorrhage and mortality(P>0.05 ).Higher rate of recovery was in favor of group A(85.4%),but not in group B(65. 2%,P<0.05).Conclusion:The combination of urokinase liquefied drainage and minimally invasive neurosurgery at the ultra - early stage may be effective and safe for the treatment of HICH with hematoma(30 -60 ml).

  • 【文献出处】 广州医学院学报 ,Academic Journal of Guangzhou Medical College , 编辑部邮箱 ,2012年04期
  • 【分类号】R743.34
  • 【被引频次】1
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