【摘要】 目的了解广东省东莞地区变应性疾病患者特异性过敏原及血清IgE水平变化,为临床提供诊疗依据。方法采用体外定性酶免疫分析法对1598例变应性疾病患者血清进行吸入物与食入物过敏原检测,同时检测总IgE水平。结果 1598例变应性疾病患者中血清总IgE阳性1480例,总阳性率为92.6%,其中以荨麻疹患者最高(96.8%)。吸入物过敏原以尘螨、粉螨、屋尘最高(19.5%),其次为蟑螂、飞蛾、蜜蜂(14.4%);食入物过敏原以草菇、冬菇、金针菇最高(11.7%),其次为虾、蟹、扇贝、干贝等(10.1%)。结论尘螨、粉螨、屋尘、草菇、冬菇、金针菇等为广东省东莞地区变应性疾病患者最主要过敏原。明确过敏原后对特异性免疫治疗具有重要指导意义。更多还原

【Abstract】 Objective To evaluate specific allergen and changes of serum IgE level in allergic disease patients of Dongguan,Guangdong to provide evidence for clinical diagnosis and treatment.Methods In vitro qualitative enzyme immune analysis was performed to detected inhaled and eaten allergens in serum of 1 598 cases of patients with allergic diseases,and total IgE level was also detected.Results In 1 598 cases of allergic disease patients,1 480 cases were positive with serum total IgE,and the positive rate was 92.6%,among whom the proportion of urticaria patients was the highest(96.8%).Among inhaled allergens,the positive rate of dust mites,flour mite and house dust was the highest(19.5%),followed by cockroaches,moths and bees(14.4%).Among eaten allergens,the positive rate of straw mushrooms,snake butter and needle mushrooms was the highest(11.7%),followed by shrimp,crab,scallops,scallops and so on(10.1%).Conclusion Dust mites,flour mite,house dust,straw mushrooms,snake butter,needle mushroom and so on might be the most common allergens,causing allergic diseases in Dongguan.Identification of allergens might be with important guiding significance for specific immune therapy.更多还原