【摘要】 目的探讨不同风险指标对急性脑梗死(ACI)的影响程度。方法选择ACI确诊患者111例(ACI组),在发病24h内检测血小板参数、凝血指标及超敏C反应蛋白(hs-CRP)、尿酸(UA)、空腹血糖(FBG)、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等参数,调查身体质量指数(BMI)、吸烟、饮酒等一般资料。以104例体检健康者作为对照组。采用Logistic回归分析各风险因素的相对危险度(OR值)。结果 Logistic回归分析显示,吸烟、LDL-C、平均血小板体积(MPV)、TC、FBG、TG、BMI、饮酒、hs-CRP、血小板分布宽度(PDW)为ACI高危因素,其OR值分别为2.527、2.036、1.570、1.478、1.456、1.345、1.128、1.103、1.080、1.062。结论吸烟、LDL-C、MPV、TC、FBG、TG、BMI、饮酒、hs-CRP、PDW均为ACI高危因素,监测其变化对预防ACI有重要意义。更多还原

【Abstract】 Objective To evaluate the effects of different risk factors on acute cerebral infarction(ACI).Methods 111 cases of patients with ACI(ACI group) were enrolled,and platelet parameters,coagulation parameters,hypersensitivity C reactive protein(hs-CRP),urea acid(UA),fasting blood glucose(FBG),triacylglycerol(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C) were determined within 24 h after morbidity.Body mass index(BMI),history of smoking and drinking alcohol were inquired.104 cases of healthy controls were enrolled as control group.Relative risk,indicated as odd ratio(OR),of all risk factors were evaluated by logistic regression.Results Logistic regression analysis demonstrated that smoking,LDL-C,mean platelet volume(MPV),TC,FBG,TG,BMI,drinking alcohol,hs-CRP and platelet distribution width(PDW) were high risk factors of ACI,with OR values of 2.527,2.036,1.570,1.478,1.456,1.345,1.128,1.103,1.080 and 1.062 respectively.Conclusion Smoking,LDL-C,MPV,TC,FBG,TG,BMI,drinking alcohol,hs-CRP and PDW might be high risk factors of ACI.It could be great significant to monitor these factors for the prevention of ACI.更多还原