【摘要】 氟化物作为防龋制剂,其广泛应用可能导致变异链球菌耐氟菌株的产生。为了解变异链球菌耐氟菌株致龋毒力的变化,学者们对其超微结构、黏附力、耐酸性、产酸性及脱矿能力等致龋相关特性进行了研究,并对耐氟菌株的致龋相关基因和其他分子生物学改变予以深入的研究和探讨。本文就此作一综述。更多还原

【Abstract】 As a caries-preventive agent,fluoride could probably lead to fluoride-resistant strains of Streptococcus mutans(S.mutans) with its wide application in the daily life.In order to understand the cariogenic changes in virulence of the fluoride-resistant strains of S.mutans,scholars conducted various studies concerning their ultrastructure,adhesion,acid resistance,acid production and demineralization ability,as well as cariogenic related genes and other molecular biological characteristics.This article was committed to review the research progress in recent years.更多还原