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成人急性小脑性共济失调13例临床研究及文献复习

Analysis of Acute Cerebellar Ataxia in 13 Adults

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【作者】 林艳陈吉相周彦兵曹国栋

【Author】 LIN Yan,CHEN Ji-xiang,ZHOU Yan-bing,CAO Guo-dong.Department of internal medicine II,the People’s Hospital of Bo’ertala zhou,Xinjiang 833400,China

【机构】 新疆博尔塔拉蒙古自治州人民医院内二科华中科技大学同济医学院附属协和医院博州分院内二科华中科技大学同济医学院附属协和医院神经科

【摘要】 目的:研究成人急性小脑性共济失调(ACA)的常见病因和临床特征。方法:对13例成人ACA患者的临床资料进行总结分析。结果:成人发病者以青壮年多见,男性多于女性;感染是ACA的主要病因;临床以头晕、共济失调为主要特征。结论:成人ACA病前多有前驱感染史,MRI检查阳性率较高,使用抗病毒、甘露醇脱水及激素治疗有效,预后良好,少数患者可能复发。

【Abstract】 Objective: To summarize the common causes and clinical features of acute cerebellar ataxia(ACA) in adults.Methods: The clinical data of 13 adults with ACA was analyzed.Results: Young adults were commonly affected in the adult-onset cases,and the incidence is higher in men than that in women.Infection is a major cause of ACA.Dizziness and ataxia are the main symptoms of adults with ACA.Conclusion: Infection is a preceding factor for adult-onset ACA.Abnormalities on brain MRI could be found in majority of patients with ACA.Antiviral drugs,mannitol and glucocorticoid are effective to control the disease.Most patients have good prognosis,whereas few cases may relapse.

【关键词】 成人急性共济失调
【Key words】 adult-onsetacute cerebral ataxia
  • 【文献出处】 神经损伤与功能重建 ,Neural Injury and Functional Reconstruction , 编辑部邮箱 ,2012年06期
  • 【分类号】R742.82
  • 【被引频次】2
  • 【下载频次】169
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