【摘要】 目的:观察倍他司汀联合丹参治疗椎-基底动脉供血不足的疗效。方法:119例椎-基底动脉供血不足(VBI)患者分为2组,对照组59例,给予丹参注射液20 mL加入0.9%氯化钠注射液250 mL静脉滴注,1次/d,疗程10 d。治疗组60例,在对照组治疗的基础上加倍他司汀口服液20 mg,2次/日。治疗前后进行经颅多普勒(TCD)检查及治疗后临床疗效评定。结果:经过10 d治疗后治疗组总有效率91.1%,优于对照组为78.0%。差异有统计学意义(P<0.05);TCD显示治疗组收缩期血流峰值流速(Vp)改善优于对照组。结论:倍他司汀口服液联合丹参注射液治疗VBI效果好,值得临床推广应用。更多还原

【Abstract】 Objective:To observe the clinical effect on vertebro-basilar insufficiency treated with Betahistine and Salvia miltiorrhiza.Methods:119 cases of vertebral-basilar insufficiency(VBI) were divided into two groups,Control Group and Treatment Group.59 patients in the Control Group were given Salvia miltiorrhiza injection 20 mL 0.9% sodium chloride injection 250 mL,intravenous drip per day and 10 days as a course;60 patients in the Treatment Group were given Salvia miltiorrhiza injection 20 mL 0.9% sodium chloride injection 250 mL,intravenous drip and Betahistine oral liquid 20 mg,2 times/day.Patients of the two groups were examined by transcranial Doppler(TCD) before and after treatment,and clinical assessment were compared after treatment.Results:After treatment,the total effective rate was 91.1% in the Treatment Group and 78.0% in the Control Group,with significantly difference(P<0.05);The peak values of blood flow velocity of vertebro-basilar was significantly better in the Treatment Group than that of the Control Group.Conclusion:This combination use to treat VBI was effective.It is worthy of clinical application.更多还原