【摘要】 目的探讨不同对比剂剂量对肝脏小结节性病变64层CT灌注参数的影响。方法对12例肝小结节患者分别用50ml、100ml对比剂以5ml/s的注射速率行64层CT灌注检查,分析病变与正常肝实质血流量(BF)比值、血容量(BV)比值、平均通过时间(MTT)比值、血管表面通透性(PS)比值、肝动脉灌注分数(HAF)比值、病灶强化峰值(PV)、病灶强化增量(PEI)和强化比值(CER)。结果 100ml组无论是病变还是正常肝实质的BV、BF、PV、PEI、CER均高于50ml组;100ml组病灶与正常肝实质的BV、BF比值及病灶的PV、PEI、CER明显高于50ml组(P<0.05)。结论大剂量对比剂(100ml)灌注扫描有助于肝脏小结节性病变的检出和进一步定性。更多还原

【Abstract】 Objective To investigate the influence of various doses of contrast agent on hepatic tuberculum minus perfusion imaging with 64-slice spiral CT. Methods Hepatic tuberculum minus perfusion imaging was performed in 12 patient with different doses of contrast agent (50 ml, 100 ml ) at 5ml/s injection rate, the ratio of blood flow (BF), blood volume (BV), mean transit time (MTT), permeability surface (PS), hepatic arterial fraction (HAF) between liver lesions and normal liver, and the peak value (PV), peak enhancement increase (PEI), contrast enhancement ratio (CER) of liver lesions were analyzed. Results With the dose of 100 ml , the BV, BF, PV, PEI, CER of liver lesions and normal liver were higher than the dose of 50 ml. The perfusion parameters with 100ml dose were higher than the dose of 50 ml in the ratio of BV and BF between liver lesions and normal liver and the PV, PEI, CER of liver lesions(P?<?0.05). Conclusion Perfusion imaging is useful both in detection and further qualitative diagnosis of hepatic tuberculum minus with the dose of 100ml.更多还原