【摘要】 目的探讨不同程度的部分脾动脉栓塞(PSE)对肝硬化伴食管静脉曲张的影响。方法 45例肝硬化伴食管静脉曲张患者随机分为A、B、C3组,分别按栓塞面积40%～60%、60%～80%、80%～100%进行PSE;手术前后B超测量门静脉(PV)及胃冠状静脉(GCV)管径及血流方向,胃镜评估食管胃底静脉曲张程度。结果除A组外,B、C组PSE后PV、GCV直径明显变小,C组最明显(P<0.01或0.05)。B、C组食管胃底静脉曲张程度比A组明显减轻(P<0.05)。发热持续时间、胸水、腹水等不良反应以C组最严重(P<0.01)。结论 PSE对肝硬化伴食管静脉曲张具有明显疗效,栓塞程度以60%～80%为最佳。更多还原

【Abstract】 Objective To investigate the effect of partial splenic embolization(PSE) on esophageal varices in patients with liver cirrhosis.Methods Fourty-five patients with liver cirrhosis and esophageal varices were divided into A,B and C groups.The PSE area was 40%~60% in group A,60%~80% in group B,and 80%~100% in group C.Diameter and flow direction of portal vein(PV) and gastric coronary vein(GCV) and degree of esophageal and gastric varices were measured by Doppler ultrasound and gastroscopy before and after operation,respectively.Results Except group A,the diameter of PV and GCV reduced remarkably after PSE in group B and C,especially in group C(P<0.01 or 0.05).The degree of esophageal and gastric varices was significantly lower in group B and C than that in group A(P<0.05).The side effects such as the duration of fever,pleural effusion,abdominal pain were more severe in group C(P<0.01) compared with other groups.Conclusion PSE is effective in the treatment of esophageal varices in patients with liver cirrhosis,with the optimal embolization area being 60%~80%.更多还原