【摘要】 以盐酸普萘洛尔为目标模板分子,通过电聚合多巴胺,在多壁碳纳米管修饰的玻碳电极表面制备了对目标分子有特异响应的分子印迹电化学传感器。利用扫描电子显微镜、循环伏安法和差示脉冲伏安法对此传感器的表面形貌及性能进行了表征,并且优化了检测条件,研究了印迹传感器对模板分子及其结构类似物的选择性响应。结果表明:此传感器具有较好的选择性响应,而且碳纳米管的存在显著提高了传感器的灵敏度。盐酸普萘洛尔的浓度在0.20～100μmol/L范围内与峰电流呈良好的线性关系;检出限为2.53×10-8mol/L(S/N=3)。此传感器还具有良好的稳定性和重现性。更多还原

【Abstract】 A sensitive molecularly imprinted electrochemical sensor was fabricated for selective detection of propranolol hydrochloride by electroploymerization of dopamine on glassy carbon electrode(GCE) modified with multi-walled carbon nanotubes(MWNTs).The electrochemical performance and morphology of the imprinted sensor were characterized by scanning electron microscope(SEM),cyclic voltammetry(CV),differential pulse voltammetry(DPV).Test conditions were optimized and the selective response to the structurally similar compounds of propranolol hydrochloride was studied.The results showed that the sensor had good selectivity and the sensitivity increased greatly due to the introduction of MWNTs.A linear relationship was obtained between the current and the concentration of propranolol hydrochloride over a range from 0.20 to 100 μmol/L,with a detection limit of 2.53×10-8 mol/L(S/N=3).Moreover,the sensor exhibited excellent stability and reproducibility.更多还原