【摘要】 目的:探讨血清可溶性B7-H4(sB7-H4)在淋巴瘤患者检测中的临床意义。方法:用ELISA夹心法检测52例淋巴瘤患者与50例健康者血清sB7-H4水平。结果:霍奇金病、非霍奇金淋巴瘤患者血清sB7-H4水平分别为(45.66±12.48μg/L、50.24±14.52μg/L)明显高于健康者水平(26.47±10.35μg/L),差异有统计学意义(P<0.01)。结论:sB7-H4与淋巴瘤的发病有关,对淋巴瘤的辅助诊断具有一定的临床意义。更多还原

【Abstract】 Objective To evaluate the clinical significance of serum soluble B7-H4(sB7-H4) in patients with lymphoma.Methods Enzyme-linked immunosorbent assay was used to detect the level of serum soluble B7-H4 in 52 patients with lymphoma,compared with 50 healthy individuals.Results The level of serum soluble B7-H4 in Hodgkin’s disease group(45.66±12.48μg/L) and non-Hodgkin’s lymphoma(50.24±14.52μg/L) was increased significantly than the control group(26.47±10.35μg/L;all P<0.01).Conclusion sB7-H4 is relevant to morbidity of lymphoma,which possess certain clinical significance in aided diagnosis of lymphoma.更多还原