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DM2患者HbA1C与血清E-选择素检测的临床价值
Clinical Value of Determination of Blood HbA1C and Serum E-Selectin Levels in Patients with Type 2 Diabetes
【摘要】 目的:探讨2型糖尿病(DM2)患者糖化血红蛋白(HbA1C)与血清E-选择素之间的相关性。方法:用高压液相色谱法检测HbA1C和酶联法检测E-选择素,分析61例DM2患者及35名正常健康人作对照的血浆HbA1C与血清E-选择素间的相关性。结果:DM2患者HbAlC水平与E-选择素水平均非常显著地高于正常人组(P<0.01),且HbA1C水平与E-选择素水平呈显著正相关(r=0.5714,P<0.01)。结论:高血糖对血清E-选择素的表达可能有促进作用。
【Abstract】 Objective To observe the correlation between blood HbA1C and E-selectin levels in patients with DM2.Methods Blood glycosylated haemoglobin(HbA1C)(with high-pressure liquid chromatograply) and serum E-selectin(with ELISA) levels were determined in 61cases of DM2 and 35 normal controls.Results Blood HbA1C,serum E-selectin levels were remarkably higher than those in controls(P<0.01),blood HbA1C level was obvious positively correlated with serum E-selectin(r=0.5714,P<0.01).Conclusion High blood glucose might promote the expression of serum E-selectin in patients with DM2.
【Key words】 type-2 Diabetes(DM2); glycosytated haemoglobins(HbAlc); E-Selectin;
- 【文献出处】 放射免疫学杂志 ,Journal of Radioimmunology , 编辑部邮箱 ,2012年03期
- 【分类号】R587.1;R446.6
- 【被引频次】1
- 【下载频次】22