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骨生化指标联检在骨质疏松诊疗中的临床意义
Clinical Significance of Biochemical Markers in Treatment of Osteoporosis
【摘要】 目的:探讨25-羟基维生素D(25-OH-VD)与抗酒石酸酸性磷酸酶(TRACP-5b)联检在骨质疏松诊疗中的意义。方法:使用英国IDS公司的试剂盒,采用酶联免疫法(ELISA),对328例中老年患者血清做25-OHVD与TRACP-5b的检测及分析。结果:25-OH-VD指标均偏低,男性(16.18±6.77)ng/ml,女性(15.16±7.87)ng/ml,男女间差异无统计学意义(P>0.05);TRACP-5b水平女性高于男性,女性(5.71±2.46)u/L,男性(4.98±1.61)u/L,差异具有统计学意义(P<0.05)。25-OH-VD与TRACP-5b两项指标比较,相关系数(r)=-0.121,两指标呈负相关,有统计学意义(P<0.05)。结论:25-OH-VD与TRACP-5b联检对骨质疏松诊疗具有重要的参考价值。
【Abstract】 Objective To discuss the meaning of 25-OH-VD and TRACP-5b insepction in the diagnosis and treatment of osteoporosis. Methods Use English ISD company’s reagent kit on 328 elderly patients serum 25-OH-VD,TRACP-5b detection by ELISA.Analysis was made based on the results.Results The concentration of 25-OH-VD were on the low levels,male 15.18±6.77ng/ml,female 15.16±7.87ng/ml.Male and female had no difference(P>0.05);The level of TRACP-5b in female group was statistically higher than that in male group.The former was 5.71±2.46u/ml,the latter was 4.98±1.61u/ml,and the difference was statistically significant(P <0.05).The two indicators of 25-OH-VD and TRACP-5b were compared,with statistical significance(P <0.05).correlation coefficient = -0.121,two negatively related.Conclusion 25-OH-VD and TRACP-5b inspection on osteoporosis diagnosis has important reference value.
【Key words】 tartrate resistand acid phosphatase 5b; 25-hybroxyvitamin D; marker; osteoporsis;
- 【文献出处】 放射免疫学杂志 ,Journal of Radioimmunology , 编辑部邮箱 ,2012年02期
- 【分类号】R580
- 【被引频次】7
- 【下载频次】131