【摘要】 目的:探讨了乳腺癌患者手术治疗前后血清CA15-3、CA50和M-CSF水平的变化及临床意义。方法:应用放射免疫分析对32例乳腺癌患者进行了手术治疗前后血清CA15-3、CA50和M-CSF检测,并与35名正常健康人作比较。结果:乳腺癌患者在手术治疗前血清CA15-3、CA50和M-CSF水平均非常显著地高于正常人组(P<0.01),经手术治疗6个月后则与正常人组比较无显著性差异(P>0.05)。结论:检测血清CA15-3、CA50、M-CSF水平的变化对乳腺癌的诊断、治疗和预后观察均具有重要的临床价值。更多还原

【Abstract】 Objective To explore the clinical significance of changes on serum CA15-3,CA50 and M-CSF levels after surgery in patients with breast cancer.Methods Serum CA15-3,CASO and M-CSF concentration from patients with breast cancer and healthy normal controls were determined by RIA.Results Before operation,the serum CA15-3,CA50 and M-CSF levels in the patients with breast cancer were significantly higher than those in controls(P<0.01),after surgery for 6 months,the serum CA15-3,CA50 and MCSF levels in the patients were no significant difference from those in controls(P>0.05).Conclusion Detection of serum CA15-3, CA50 and M-CSF levels after operation might be of prognostic importance in patients with breast cancer.更多还原