【摘要】 目的比较放射性核素骨显像与磁共振背景抑制全身弥散加权成像(MR WB-DWIBS)对骨转移瘤的诊断效能。方法 35例经病理证实的恶性肿瘤患者,均于2周内先后行放射性核素骨显像和WB-DWIBS,对两种检查结果进行分析,比较两者对骨转移瘤诊断的灵敏度及特异性。结果两种检查方法共检出病灶106个,最终经临床确诊骨转移灶64个,其中核素骨显像检出转移灶61个,WB-DWIBS共检出转移灶56个。放射性核素骨显像和WB-DWIBS诊断骨转移瘤的灵敏度分别为95.3%和87.5%,差异无统计学意义(P>0.05);特异性分别为71.4%和90.5%,差异有统计学意义(P<0.05)。结论放射性核素骨显像与磁共振WB-DWIBS成像诊断骨转移瘤各有特点,联合应用可提高诊断正确性。更多还原

【Abstract】 Objective To compare the diagnostic efficacy of radionuclide bone scan(BS)with Whole Body MR diffusion weighted imaging with background suppression(MR WB-DWIBS)for the detection of malignant bone metastases.Methods Totally 35 patients with malignant tumors were enrolled.All the cases underwent BS and WB-DWIBS within two weeks.The results of the above-mentioned examinations were compared,and the sensitivity and specificity between them were analyzed with chi-square test.Results A total of 106 abnormal foci were identified from BS and/or WB-DWIBS,and 64 of them were diagnosed as foci of bone metastases.61 bone metastatic lesions were detected by BS and 56 by DWIBS.The diagnostic sensitivity of BS and WB-DWIBS were 95.3% and 87.5%(P>0.05),while the specificity was 71.4% and 90.5%(P<0.05),respectively.Conclusion Radionuclide bone scan and MR WB-DWIBS have their respective advantages in the detection of malignant bone metastases.Combination of radionuclide bone scan and MR WB-DWIBS will improve the diagnostic accuracy in bone metastasis detection.更多还原