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孟鲁司特钠佐治毛细支气管炎30例疗效观察
Montelukast in the Treatment of Bronchiolitis: A Report of 30 Cases
【摘要】 目的:观察口服孟鲁司特钠佐治毛细支气管炎的临床疗效。方法:60例毛细支气管炎患儿随机分为两组,治疗组30例,采用常规治疗加用孟鲁司特钠,年龄1.5~6个月孟鲁司特钠2 mg/d,6~20个月孟鲁司特钠4 mg/d,疗程4周;对照组30例,仅采用常规治疗。比较两组患儿疗效及症状、体征改善时间。结果:治疗组总有效率96.6%,高于对照组86.6%,两组比较差异有统计学意义(χ2=7.26,P<0.05)。治疗组气促缓解时间、哮鸣音消失时间、湿啰音消失时间、咳嗽消失时间均短于对照组,差异均有统计学意义(P<0.01)。结论:口服孟鲁司特钠辅助治疗毛细支气管炎疗效确切,且安全方便。
【Abstract】 Objective:To observe the curative effect of montelukast in patients with bronchiolitis.Methods: Randomly 60 cases of infants with bronchiolitis were divided into two groups.The treatment group(n=30) received conventional therapy in addition to montelukast 2 mg once daily in infants 1.5~6 months of age and 4 mg once daily in infants 6~20 months of age for four weeks.The control group(n=30) received routine therapy only.The effects were evaluated and compared.Results: The total effective rate of the treatment group(96.6%) was higher than that of the control group(86.6%),the difference was significant(χ~2=7.26,P<0.05).Conclusions: Oral administration of montelukast is effective,secure and convenient for bronchiolitis treatment.
- 【文献出处】 儿科药学杂志 ,Journal of Pediatric Pharmacy , 编辑部邮箱 ,2012年06期
- 【分类号】R725.6
- 【被引频次】4
- 【下载频次】32