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支气管内超声两种回声特征在判断肺部周围型病灶良恶性中的应用

Differential diagnosis of malignant and benign peripheral pulmonary lesions based on two characteristic echo features of endobronchial ultrasonography

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【作者】 黄禹陈正贤任红岩何碧芳黎秀玉

【Author】 HUANG Yu,CHEN Zhengxian,REN Hongyan,HE Bifang,LI Xiuyu Department of Respiratory Diseases,Guangdong General Hospital,Guangzhou 510080,China

【机构】 广东省人民医院呼吸内科

【摘要】 目的评估将支气管内超声(EBUS)两种简易的回声特征应用于判断肺周围型病灶良恶性的可行性。方法分析102名接受EBUS检查的肺周围型病变患者的EBUS图像,了解这两种回声特征对周围型肺癌诊断的敏感性和特异性。结果晕环征,实性低回声是提示周围型病灶为恶性的两种回声特征。实性低回声在诊断恶性病变时敏感性较高(89.46%),特异性也较高(83%),晕环征的敏感性为69.51%,特异性为65%。只要存在任何一种回声特征,诊断恶性的敏感性可达94.6%;两种回声特征同时存在时,诊断恶性的特异性可达93%。结论对于常规支气管镜检查未能显示的周围型病灶,我们通过EBUS的这两种回声特征可较为快速、准确的诊断周围型肺癌。

【Abstract】 Objective To assess the feasibility of endobronchial ultrasonography(EBUS) in the differential diagnosis of malignant and benign lesions based on the two characteristic echo features of malignancy.Methods EBUS images from 102 patients undergoing bronchoscopy for peripheral lung lesions were analyzed.The sensitivity and specificity were determined for each echo feature,namely the halo sign and low-level echoes that indicated malignancy,or their combination in diagnosing malignant and benign lesions.Results Low-level echoes showed a sensitivity of 89.46% and a specificity of 83% in the diagnosis of malignancy,both higher than those of the halo sign(69.51% and 65%,respectively).The presence of either of the two echo features had a diagnostic sensitivity of 94.6% for malignant lesions,and the coexistence of the two features had a specificity of 93% for a diagnosis of malignant lesions.Conclusion EBUS is a useful adjunctive modality for lung cancer diagnosis,especially in cases where peripheral lung lesions are invisible in conventional bronchoscopy.

【基金】 广东省自然科学基金(S2011010001278)
  • 【文献出处】 南方医科大学学报 ,Journal of Southern Medical University , 编辑部邮箱 ,2012年07期
  • 【分类号】R445.1
  • 【被引频次】14
  • 【下载频次】129
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