尼莫地平治疗脑出血后缺血性脑损伤的疗效分析

【摘要】 目的探讨尼莫地平在脑出血后缺血性脑损伤中的临床疗效。方法以广东省博罗县博罗人民医院神经外科2011年1月～2012年3月收治的84例脑出血患者为研究对象,随机分为尼莫地平组和常规治疗组。尼莫地平组在常规治疗的基础上每天静脉滴注10mg尼莫地平,观察比较两组患者神经功能损伤情况、BI评分以及两组患者的临床治疗效果。结果尼莫地平组在治疗后临床神经功能缺损评分和BI评分的改善明显优于常规治疗组,差异有统计学意义(P<0.05);尼莫地平组患者临床治疗效果明显优于常规治疗组,差异有统计学意义(P<0.05)。结论应用尼莫地平能有效减轻脑出血患者缺血性脑损伤的程度,提高脑出血的治疗效果,值得临床推广。更多还原

【Abstract】 Objective To investigate the clinical treatment effect for nimodipine in the treatment of cerebral hemorrhage after ischemic brain injury.Methods 84 cases of patients with intracerebral hemorrhage admitted to hospital from January 2011 to March 2012 were chosen as the research object.They were randomly divided into two groups:the nimodipine group and the conventional therapy group.The nimodipine group was taken with daily intravenous infusion of 10 mg nimodipine on the basis of the conventional treatment.The neurological deficit situation,the BI score,and clinical treatment for the two groups were compared.Results The improvement of the clinical neurological deficit scores after treatment and the BI scores for the nimodipine group was significantly better than the conventional therapy group(P<0.05).The clinical therapeutic effect of nimodipine group was significantly superior to the conventional therapy group(P<0.05).Conclusion The application of nimodipine can effectively reduce the extent of ischemic brain damage in patients with cerebral hemorrhage,and improve the effect of cerebral hemorrhage treatment,it is worthy of promotion.更多还原