甲强龙治疗百草枯中毒的临床疗效观察

【摘要】 目的观察早期大剂量甲基氢化泼尼龙冲击治疗百草枯(PQ)中毒患者病死率、肺纤维化发生率的影响。方法将本院2003～2009年收治的100例口服PQ中毒患者,分为对照组50例:常规给予洗胃、血液灌流治疗;治疗组50例:在常规洗胃、血液灌流治疗基础上,早期给予大剂量甲基氢化泼尼龙冲击治疗。结果早期大剂量糖皮质激素治疗明显提高了百草枯中毒的治愈率,降低了病死率和肺纤维化发生率。结论早期大剂量甲基氢化泼尼龙冲击治疗可改善PQ中毒患者的预后,值得临床推广。更多还原

【Abstract】 Objective To observe the methyl hydrogenated early high-dose methylprednisolone pulse therapy with paraquat(PQ) poisoning death rates,incidence of pulmonary fibrosis effects.Methods 2003～2009 admitted to our hospital in 100 cases of poisoning by oral administration of PQ,is divided into a control group of 50 cases:General,blood perfusion therapy of gastric lavage;treatment group 50:conventional gastric lavage,hemoperfusion treatment on the basis of earlier hydrogen of high dose methylprednisolone pulse therapy.Results Early high-dose corticosteroids treatment significantly increased the cure rate of paraquat poisoning,reducing the incidence of mortality and pulmonary fibrosis.Conclusion Methyl-hydrogen early high-dose methylprednisolone pulse therapy can improve the prognosis of PQ poisoning,and clinical outreach.更多还原