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活性肽构效关系的研究进展
Progress of structure-activity relationship of bioactive peptides
【摘要】 文章主要综述了活性肽物质结构与功效关系的研究进展,为定向合成、改造、开发具有相关生物活性的多肽类产品提供依据。通过查阅整理相关文献报道,阐述了血管紧张素转化酶抑制肽、抗氧化肽和抗菌肽的构效关系的研究进展。活性肽蕴藏着巨大的开发潜力,是一类重要的新药来源,活性肽构效关系的研究对其发展至关重要。
【Abstract】 In this review,the progress of structure-activity relationship of bioactive peptides was summarized,which provides the basis for the stereospecific synthesis,transformation and development of bioactive peptides.According to latest related records,the progress in studies of structure-activity relationship of ACE-inhibitory peptides,antioxidant peptides and antibacterial peptides were elaborated.As a kind of important sources of new drugs,bioactive peptides have tremendous potential for development and the studies on structure-activity relationship of bioactive peptides play a significant role in it.
【Key words】 Active peptides; ACE-inhibitory peptides; Antioxidant peptides; Antibacterial peptides; Structure-activity relationship;
- 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2012年10期
- 【分类号】R96
- 【被引频次】14
- 【下载频次】828