【摘要】 目的通过研究高血压合并缺血性脑卒中的肾功能状态,分析肾功能损伤与脑卒中的关系。方法回顾性分析我科治疗的高血压合并缺血性脑卒中患者的临床资料,比较不同肾功能患者的临床情况,分析其发生缺血性脑卒中的危险度。结果重度肾功能受损组的年龄、血压和病程均高于正常对照组(P<0.05或P<0.01);轻度和中度肾功能受损组的病程亦长于正常对照组(P<0.01);各组间性别比、吸烟史、高脂血症和2型糖尿病差异均无统计学意义。重度肾功能受损组患者发生缺血性脑卒中的危险度最高,显著高于正常组(P<0.05),中度肾功能受损组的患者危险度次之,亦高于正常组(P<0.05),轻度肾功能受损组患者发生脑卒中的危险度与正常对照组相似(P>0.05)。结论高血压的治疗应重视肾脏等靶器官的损害,及早干预治疗并延缓肾功能的恶化,降低缺血性脑卒中的发生率。更多还原

【Abstract】 Objective To research the renal functional status of the patients with hypertension combined with cerebral arterial thrombosis and analyze the relationship between renal function lesion and hypertension combined with cerebral arterial thrombosis.Methods A retrospective study was conducted in patients with hypertension combined with cerebral arterial thrombosis to compare the clinical setting of different patients with renal function lesion and analyze the risks of suffering from cerebral arterial thrombosis.Results The ages,blood pressures and disease course of the patients with severe renal function lesion were higher than that of the patients in the control group(P <0.05 或 P <0.01).The disease courses of the patients with midrange or slight renal function lesion were longer than the patients in the control group(P < 0.01).There were no statistical differences about the patients’ gender,smoking history,hyperlipemia and diabetes II.The patients with severe renal function lesion had the highest risks of suffering from cerebral arterial thrombosis,which were significantly higher than that of the patients in the normal group and the patients with midrange renal function lesion.The risks of suffering from cerebral arterial thrombosis for the patients with midrange renal function lesion were higher than the patients in normal group(P <0.05).The risks of suffering from cerebral arterial thrombosis for the patients with slight renal function lesion were similar with those of the patients in the normal group(P >0.05).Conclusion Renal function lesion should be stressed in the treatment of the patients with hypertension to postpone the renal function deterioration and decrease the risks of causing cerebral arterial thrombosis.更多还原