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脑内原发性淋巴瘤的诊断及鉴别诊断

MRI diagnosis and differentiation of primary cerebral lymphoma

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【作者】 吴礼明徐丽艳殷敏敏余永强

【Author】 Wu Liming,Xu Liyan,Yin Minmin,et al Department of Radiology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China

【机构】 安徽医科大学第一附属医院放射科

【摘要】 目的分析免疫功能正常者脑内原发性淋巴瘤PCL的MRI表现,提高MRI对该病的正确诊断率。方法收集经病理及免疫组化检查确诊的9例PCL患者资料,回顾性分析其临床特点及MRI表现。结果 9例中8例位于小脑幕上,1例位于小脑幕下。颅内PCL MRI表现为以等及稍长T1信号,T2WI信号不高,呈等、低及稍高信号,2例内见明显长T1长T2信号囊变坏死,邻近脑实质及脑室轻度受压移位,9例肿块病灶周围均可见长T1长T2信号水肿带;增强扫描后肿块明显强化,呈"棉花团状"或"手握拳样"改变,9例均未见邻近颅骨受累。结论 MRI对颅内PCL的诊断有重要参考价值,但其与其他颅内肿瘤有着相似之处,确诊仍需依赖于病理学检查。

【Abstract】 Objective To analyze MRI features of primary cerebral lymphoma(PCL),to improve the diagnosis and differentiation of the disease.Methods The clinical manifestation and the MRI appearances of 9 patients with pathologically proved PCL were analyzed retrospectively.Results Among 9 patients,8 patients located above the tentorium,1 under the tentorial.The intracranial PCL manifested as iso-intensity and slight hyper-intensity on T1WI,no hyper-intensity was found on T2WI,PCL manifested as slight hypo-intensity,iso-intensity and slight hyper-intensity on T2WI,PCL was solid tumor,cystic degeneration was seen in 2 cases,and mild peritumoral edema and space-occupying effect were seen.After the contrast agent was injected,PCL was enhanced markedly,manifested as "cotton wool" or "fist-like",and the adjacent bones were not involved in all 9 cases.Conclusion MRI has important reference value in the diagnosis of PCL,but final diagnosis still depends on the pathological examination.

  • 【文献出处】 安徽医学 ,Anhui Medical Journal , 编辑部邮箱 ,2012年07期
  • 【分类号】R739.4
  • 【被引频次】6
  • 【下载频次】90
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