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多靶点酪氨酸激酶抑制剂的研究概况

Research profiles of multi-target tyrosine kinase inhibitor

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【作者】 宋宇红

【Author】 SONG Yu-hong Anhui provincial hospital,Hefei 230001,Anhui

【机构】 安徽省立医院

【摘要】 肿瘤疾病的药物治疗一直是医学界的困扰,因为机体的多个受体都与发病有关,并且关系到病情的发展,此外信号通路也是相关因素。经过临床长期病理研究和药理分析,多靶点制剂被专家、学者认可,其较单靶点制剂具有使用优势,可以通过干扰肿瘤信号转导从而防治疾病。该文将把此类制剂按照化学结构划分,概述多靶点氨酸激酶抑制剂的新进展。

【Abstract】 Drug treatment of neoplastic diseases has been the troubles of the medical profession,because of the body’s receptors and the pathogenesis of and relationship to the development of the disease.In addition,signaling pathways are also relevant factors.Clinical long-term pathological and pharmacological analysis,multi-target agents to be experts,scholars recognized by its more single-target agents have to use the advantages,you can to fight disease by interfering with the tumor signal transduction.This article will refer to such agents which are divided in accordance with the chemical structure to illustrate the new progress of the multi-target tyrosine kinase inhibitor.

  • 【文献出处】 安徽卫生职业技术学院学报 ,Journal of Anhui Health Vocational & Technical College , 编辑部邮箱 ,2012年04期
  • 【分类号】R979.1
  • 【下载频次】171
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