【摘要】 目的就产前诊断为标记染色体的胎儿,分析标记染色体与胎儿表型的关系。方法对5320例产前诊断的羊水,脐带血样本行G显带染色体核型分析。结果检出3例新发标记染色体,其中两例嵌合型,且胎儿均伴有不同程度的畸形。结论细胞遗传学对标记染色体进行检测,结合来源分析,以提供有效的产前诊断信息。更多还原

【Abstract】 Objective:To analysis the relationship between marker chromosomes and the fetal phenotype on 3 samples from prenatal diagnoses.Methods:G-banding were perform on 5320 prenatal diagnosis from amniotic fluid and cord blood sample.Results:Three de novo cases of marker chromosome were checked out with fetal abnormalities.Two of which showed mosaic karyotypes.Conclusion:Cytogenetics characterize precisely marker chromosome,and supplies the effective prenatal diagnosis information.更多还原