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对常规IVF授精后4小时未排出第二极体的卵母细胞行补救ICSI

Rescue ICSI of oocytes that failed to extrude the second polar body 4h post-insemination in conventional IVF.

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【作者】 罗清炳张昌军杨梅徐鸿毅

【Author】 LUO Qing-bing,ZHANG Chang-jun,YANG Mei,XU Hong-yi.(Reproductive Medicine Research Center,Renmin Hospital,Yunyang Medical College,Shiyan Hubei 442000,China)

【机构】 湖北省郧阳医学院附属人民医院生殖医学中心

【摘要】 目的比较常规IVF授精后4h和20h补行卵胞浆内单精子注射(rescue ICSI)的效果。方法回顾分析2006年1月-2007年12月在我院生殖医学中心接受常规IVF治疗的21例非男性因素不育患者,授精后4h行补救ICSI,并与另组实施的18个常规IVF授精后20h行补救ICSI周期进行比较。结果 4h补救ICSI组的受精率为76.3%,高于20h补救ICSI组(53.0%),有统计学意义(P<0.05)。4h补救ICSI组中11例临床妊娠(52.3%),其中2个双胎,8个单胎和一个流产。而20h补救ICSI组无一例妊娠。结论和授精后20h行补救ICSI相比,授精后4h行补救ICSI可以获得较好的受精率、妊娠率和种植率。

【Abstract】 Obstract: Objective To evaluate the clinical effect of rescue ICSI of oocytes failed to fertility after 4 and 20 hours in conventional IVF.Methods: From January 2006 to june 2007,21 patients without male infertility factors were received rescue ICSI after 4 hours.The other group about 18 patients.Results: The fertilition rate of 4 and 20 hours’group account for 76.3% and 53.0% respectively.The differences were significance(P<0.05).11 patients achieved pregnancy in the former group including 2 twins,8 sigletions and 1 abortion,no pregnancy in the 20 hours’group.Conclusion: Compared to rescue ICSI after 20 hours’insemination in conventional IVF.We can achieve better fertilization rate,implantation rate and pregnancy rate.

【关键词】 受精失败卵母细胞极体原核补救ICSI
【Key words】 Fertilization failureOocytesPolar bodyPronucleiRescue ICSI
  • 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2011年07期
  • 【分类号】R714.8
  • 【被引频次】2
  • 【下载频次】126
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